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臓器特異的遺伝子編集によるRasドライバー発癌制御遺伝子座解析系の実証的構築

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臓器特異的遺伝子編集によるRasドライバー発癌制御遺伝子座解析系の実証的構築

Material type
文書・図像類
Author
鈴木, 昇
Publisher
三重大学
Publication date
2022-05-20
Material Format
Digital
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application/pdf2019年度~2021年度科学研究費補助金(基盤研究(C))研究成果報告書19K06456

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Ras活性化変異後の発癌プロセスに特化した量的遺伝子座解析動物システムを開発し、発癌物質による肺癌モデルのようにRas変異前のプロセス(発癌物質の代謝、DNA修復、体細胞組み換えなどホスト因子による反応など)の影響を最小化した。これにより、これまで見出せなかった肺癌細胞で発現する遺伝子18個(Srs...

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Material Type
文書・図像類
Author/Editor
鈴木, 昇
Author Heading
Publication, Distribution, etc.
Publication Date
2022-05-20
Publication Date (W3CDTF)
2022-05-20
Alternative Title
Empirical construction of organ-specific gene editing system for analysing Ras driver carcinogenesis control locus
Text Language Code
jpn