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文書・図像類

免疫抑制回避機構を有するoff-the-shelf型CAR導入γδT細胞

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免疫抑制回避機構を有するoff-the-shelf型CAR導入γδT細胞

Material type
文書・図像類
Author
加藤, 琢磨ほか
Publisher
三重大学
Publication date
2023-05-29
Material Format
Digital
Capacity, size, etc.
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application/pdf2020年度~2022年度科学研究費補助金(基盤研究(C))研究成果報告書20K07674

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Summary, etc.:

本研究ではγδ型T細胞のアロ未反応性を利用したoff-the-shelf化を介して固形がんに対するCAR-T細胞療法のPOCを確立する目的で、細胞内にCD28とCD3zetaのシグナル伝達ドメインを含むCEA特異的CARならびにGITRLを同時に発現するγδ型T細胞(それぞれ、CEA.CAR-gdT...

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Digital

Material Type
文書・図像類
Author/Editor
加藤, 琢磨
王, 立楠
Publication, Distribution, etc.
Publication Date
2023-05-29
Publication Date (W3CDTF)
2023-05-29
Alternative Title
Off-the-shelf immunotherapy with CAR-gamma delta T cells
Text Language Code
jpn