文書・図像類

MUC5B過剰発現マウスを用いた肺線維症の細菌叢異常におけるムチンの役割の検討

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MUC5B過剰発現マウスを用いた肺線維症の細菌叢異常におけるムチンの役割の検討

Material type
文書・図像類
Author
Gabazza, Estebanほか
Publisher
三重大学
Publication date
2023-05-17
Material Format
Digital
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application/pdf2020年度~2022年度科学研究費補助金(基盤研究(C))研究成果報告書20K08564

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Summary, etc.:

MUC5Bの単塩基多型(rs35705950)を有する患者では肺線維症の発症の危険度が約20倍になることが示されている。また、肺内細菌叢のアンバランスは肺線維症の病態の進行に関わっていると知られている。そこで、我々はMUC5Bの過剰発現TGマウス及び野生型マウスを用いて肺内細菌叢の特徴と肺線維症の病...

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Digital

Material Type
文書・図像類
Author/Editor
Gabazza, Esteban
戸田, 雅昭
竹下, 敦郎
安間, 太郎
小林, 哲
Publication, Distribution, etc.
Publication Date
2023-05-17
Publication Date (W3CDTF)
2023-05-17
Alternative Title
Investigating the role of mucin in pulmonary fibrosis-associated microbiota dysbiosis using MUC5B overexpressing mice
Text Language Code
jpn