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文書・図像類

エネルギー代謝に注目した多機能遺伝子改変γδT細胞の追求

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エネルギー代謝に注目した多機能遺伝子改変γδT細胞の追求

Material type
文書・図像類
Author
石原, 幹也ほか
Publisher
三重大学
Publication date
2023-06-05
Material Format
Digital
Capacity, size, etc.
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application/pdf2020年度~2022年度科学研究費補助金(基盤研究(C))研究成果報告書20K07656

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Summary, etc.:

αβ-TCRとCD8を発現する遺伝子改変γδT細胞(GMC)は、抗原特異的細胞傷害性と優れた持続性を示した。GMCのサイトカイン分泌は非遺伝子改変γδ-T細胞(NGMC)よりもATP合成酵素阻害剤により強く阻害された。メタボロームおよびトランスクリプトーム解析により、GMCはTCAサイクルと酸化的リ...

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Digital

Material Type
文書・図像類
Author/Editor
石原, 幹也
三輪, 啓志
Publication, Distribution, etc.
Publication Date
2023-06-05
Publication Date (W3CDTF)
2023-06-05
Alternative Title
Pursuit of multifunctional gene-modified gamma-delta T cells focusing on energy metabolism
Text Language Code
jpn