ドキソルビシンはミトコンドリアDNAへ集積しAlas1依存性のヘム合成を破綻させることでフェロトーシスと心毒性を引き起こす

Name of awarding university/degree: 九州大学,博士（医学）,DOCTOR OF PHILOSOPHY (Medical Science)

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Material Type: 博士論文
Title: ドキソルビシンはミトコンドリアDNAへ集積しAlas1依存性のヘム合成を破綻させることでフェロトーシスと心毒性を引き起こす
Author/Editor: 阿部, 巧
Author Heading: 阿部, 巧アベ, コウ
Publication Date: 2023-03-20
Publication Date (W3CDTF): 2023-03-20
Alternative Title: Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis
Contributor: 山浦, 健
塩瀬, 明
久場, 敬司
Degree grantor/type: 九州大学
Date Granted: 2023-03-20
Dissertation Number: 17102甲第16479号
Degree Type: 博士（医学）
DOCTOR OF PHILOSOPHY (Medical Science)
Text Language Code: eng
Target Audience: 一般
Rights (production): やむを得ない事由により本文ファイル非公開 (2)
Public access to the fulltext file is restricted for unavoidable reason (2)
Is Version Of (DOI): 10.1126/scisignal.abn8017
https://hdl.handle.net/2324/6787509
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 九州大学 : 九州大学学術情報リポジトリ