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文書・図像類

迅速かつ効率的な遺伝子導入法を用いた概日リズム発振・同調メカニズムの解明

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迅速かつ効率的な遺伝子導入法を用いた概日リズム発振・同調メカニズムの解明

Material type
文書・図像類
Author
早坂, 直人ほか
Publisher
近畿大学
Publication date
2008-01-01
Material Format
Digital
Capacity, size, etc.
-
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Note (General):

研究種目:基盤研究(C); 研究期間:2007~2008; 課題番号:19590235;研究分野:医歯薬学; 科研費の分科・細目:基礎医学・環境生理学Research Paperapplication/pdf

Related materials as well as pre- and post-revision versions

http://rns.nii.ac.jp/nr/1000080368290

http://rns.nii.ac.jp/nr/1000010291080

http://rns.nii.ac.jp/nr/1000030398119

Detailed bibliographic record

Summary, etc.:

GeneChip により網羅的に採取した概日振動遺伝子群の中で、発現が組織特異的で且つ機能が特に注目される遺伝子改変動物を計7種類作製した。そのひとつRGS 遺伝子の発現を抑制する2種の独立のノックダウンマウスを作製した。双方のマウスに共通して、活動リズムの周期変化、肝臓、膵臓の病理学的異常と糖代謝...

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  • Kindai University Academic Resource Repository

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Bibliographic Record

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Digital

Material Type
文書・図像類
Author/Editor
早坂, 直人
中島, 芳浩
明石, 真
Publication, Distribution, etc.
Publication Date
2008-01-01
Publication Date (W3CDTF)
2008-01-01
Alternative Title
Analyses of molecular mechanisms underlying circadian rhythm generation and synchronization by rapid and efficient gene transduction in vivo.
Periodical title
科学研究費補助金研究成果報告書 (2008. )
Pages
1-4