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血管新生阻害薬の耐性研究

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血管新生阻害薬の耐性研究

Material type
文書・図像類
Author
西尾, 和人ほか
Publisher
近畿大学
Publication date
2009-01-01
Material Format
Digital
Capacity, size, etc.
-
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研究種目：基盤研究（A）研究期間：2007～2009課題番号：19209018研究分野：医歯薬学科研費の分科・細目：境界医学・応用薬理学Research Paperapplication/pdf

Related materials as well as pre- and post-revision versions

http://rns.nii.ac.jp/nr/1000010208134

http://rns.nii.ac.jp/nr/1000020441074

Detailed bibliographic record

Summary, etc.：

VEGFR2チロシンキナーゼ阻害薬耐性血管内皮細胞の樹立に国内外で初めて成功し、分子細胞学的な血管新生阻害薬の耐性メカニズムの一つを明らかにした。薬剤耐性において血管内皮細胞のVEGFR2発現抑制、およびVEGFR2シグナル依存からのエスケープ現象が耐性メカニズムであることを同定した。また、CEP(...

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Digital

Material Type
文書・図像類
Title
血管新生阻害薬の耐性研究
Author/Editor
西尾, 和人
荒尾, 徳三
Author Heading
西尾, 和人
荒尾, 徳三
Publication, Distribution, etc.
近畿大学
Publication Date
2009-01-01
Publication Date (W3CDTF)
2009-01-01
Alternative Title
Mechanism of acquired drug resistance to VEGFR2 tyrosine kinase inhibitor in vascular endothelial cells
Periodical title
科学研究費補助金研究成果報告書 (2009. )
Pages
1-6