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ヒストン脱アセチル化酵素阻害剤による初期化促進の分子機構解明とその応用

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ヒストン脱アセチル化酵素阻害剤による初期化促進の分子機構解明とその応用

Material type
文書・図像類
Author
岸上, 哲士ほか
Publisher
近畿大学
Publication date
2009-01-01
Material Format
Digital
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研究種目:基盤研究(B)研究期間:2007~2009課題番号:19380161研究分野:農学科研費の分科・細目:畜産学・獣医学・応用動物科学Research Paperapplication/pdf

Related materials as well as pre- and post-revision versions

http://rns.nii.ac.jp/nr/1000010291064

http://rns.nii.ac.jp/nr/1000040360672

http://rns.nii.ac.jp/nr/1000010298937

Detailed bibliographic record

Summary, etc.:

世界初のクローンヒツジ「ドリー」の報告以来、クローン動物の作出効率は動物種によらずわずか数%と低率であった。本研究代表者は、クローン胚をヒストン脱アセチル化酵素阻害剤(HDACi)、トリコスタチンA(trichostatin A, TSA)で処理することでクローンマウスの作出効率が大幅に改善されるこ...

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Digital

Material Type
文書・図像類
Author/Editor
岸上, 哲士
若山, 照彦
佐伯, 和弘
Publication, Distribution, etc.
Publication Date
2009-01-01
Publication Date (W3CDTF)
2009-01-01
Alternative Title
Elucidation of the molecular mechanism underlying the enhancement of somatic-cell reprogramming by a histone deacetylase inhibitor, and its applications
Periodical title
科学研究費補助金研究成果報告書 (2009. )
Pages
1-5