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Rac2発現の制御機構及びRac2依存的抗HIV-1感染機序の解明

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Rac2発現の制御機構及びRac2依存的抗HIV-1感染機序の解明

Material type
文書・図像類
Author
博多, 義之
Publisher
近畿大学
Publication date
2010-01-01
Material Format
Digital
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研究種目：若手研究（B）; 研究期間：2009～2010; 課題番号：21790450; 研究分野：医歯薬学; 科研費の分科・細目：基礎医学・ウイルス学Research Paperapplication/pdf

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https://kaken.nii.ac.jp/ja/r/30344500

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Summary, etc.：

研究成果の概要（和文）：HIV-1感染感受性には個人差がある。rac2遺伝子は感染抵抗性遺伝子であり、Rac2の発現が高いヒトはより感染抵抗性になる。本研究ではRac2高発現を制御する１塩基を同定した。また、Rac2の高発現により感染に必須のHIV-1受容体CCR5の発現が減少し、かつ感染阻害活性を...

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Digital

Material Type
文書・図像類
Title
Rac2発現の制御機構及びRac2依存的抗HIV-1感染機序の解明
Author/Editor
博多, 義之
Author Heading
博多, 義之
Publication, Distribution, etc.
近畿大学
Publication Date
2010-01-01
Publication Date (W3CDTF)
2010-01-01
Alternative Title
Analysis of rac2 gene expression and its role on anti-HIV-1 restriction
Periodical title
科学研究費補助金研究成果報告書 (2010. )
Pages
1-4