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レトロウイルス誘発抗原特異的CD8T細胞機能不全機構の解明

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レトロウイルス誘発抗原特異的CD8T細胞機能不全機構の解明

Material type
文書・図像類
Author
高村, 史記
Publisher
近畿大学
Publication date
2011-01-01
Material Format
Digital
Capacity, size, etc.
-
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研究種目：若手研究（B）; 研究期間：2010～2011; 課題番号：22790441; 研究分野：医歯薬学; 科研費の分科・細目：基礎医学・ウイルス学Research Paperapplication/pdf

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http://kaken.nii.ac.jp/d/r/90528564.ja.html

Detailed bibliographic record

Summary, etc.：

研究成果の概要（和文）：ウイルス等の持続感染個体では、ウイルス特異的メモリーCD8T 細胞に対して特異抗原による継続的な刺激が繰り返されることにより種々の抑制性受容体の発現が持続し、結果T細胞機能が低下するいわゆる疲弊（exhaustion）が起こる。マウスに持続的なウイルス血症とそれに引き続く致死...

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Digital

Material Type
文書・図像類
Title
レトロウイルス誘発抗原特異的CD8T細胞機能不全機構の解明
Author/Editor
高村, 史記
Author Heading
高村, 史記
Publication, Distribution, etc.
近畿大学
Publication Date
2011-01-01
Publication Date (W3CDTF)
2011-01-01
Alternative Title
Retrovirus evasion of CD8^+ T cell immunity
Periodical title
科学研究費補助金研究成果報告書 (2011. )
Pages
1-5