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プロスタグランジンD合成酵素の分子内SS結合形成による睡眠誘発物質放出機構の解明

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プロスタグランジンD合成酵素の分子内SS結合形成による睡眠誘発物質放出機構の解明

Material type
文書・図像類
Author
島本, 茂
Publisher
近畿大学
Publication date
2013-01-01
Material Format
Digital
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研究種目:若手研究(B); 研究期間:2012~2013; 課題番号:24790055; 研究分野:医歯薬学; 科研費の分科・細目:物理系薬学Research Paperapplication/pdf

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http://kaken.nii.ac.jp/d/r/00610487.ja.html

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Summary, etc.:

研究成果の概要(和文): リポカリン型プロスタグランジンD合成酵素(L-PGDS)は, 睡眠調節薬開発のターゲットとして多くの研究が為されてきたが, 生成物(PGD2)の放出過程のメカニズムは明らかになっていない. 本研究では, L-PGDSのPGD2認識・放出機構を熱力学的および構造生物学的に明ら...

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Digital

Material Type
文書・図像類
Author/Editor
島本, 茂
Author Heading
Publication, Distribution, etc.
Publication Date
2013-01-01
Publication Date (W3CDTF)
2013-01-01
Alternative Title
Product release mechanism of Lipocalin—type Prostaglandin D synthase
Periodical title
科学研究費助成事業研究成果報告書 (2013. )
Pages
1-5