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幹細胞機能亢進を制御するNotch/解糖系経路解明による新規間葉系幹細胞創製

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幹細胞機能亢進を制御するNotch/解糖系経路解明による新規間葉系幹細胞創製

Material type
文書・図像類
Author
森山, 博由ほか
Publisher
近畿大学
Publication date
2017
Material Format
Digital
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Note (General):

研究種目:基盤研究(C); 研究期間:2014~2016; 課題番号:26501007; 研究分野:幹細胞生物学・皮膚科学; 科研費の分科・細目:Research Paperapplication/pdf

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https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26501007/

Detailed bibliographic record

Summary, etc.:

研究成果の概要(和文):hADSCを、溶存酸素濃度を指標として低酸素培養することにより、新規のhADSCの亜集団を同定した。この時、解糖系が亢されることが認められた。このとき、これらの集団では、低酸素応答因子HIF非依存的なNotchシグナルの活性化が引き起こされていた。Notchシグナルは解糖系亢...

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Digital

Material Type
文書・図像類
Author/Editor
森山, 博由
森山, 麻里子
Publication, Distribution, etc.
Publication Date
2017
Publication Date (W3CDTF)
2017
Alternative Title
Isolation of a novel human-mesenchymal stem cells based on the mechanism of Notch/ glycolytic pathway.
Periodical title
科学研究費助成事業研究成果報告書 (2016)
Pages
1-6