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文書・図像類

接着分子を標的とする肺気腫治療の創薬シーズ探索

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接着分子を標的とする肺気腫治療の創薬シーズ探索

Material type
文書・図像類
Author
萩山, 満
Publisher
近畿大学
Publication date
2017
Material Format
Digital
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研究種目:若手研究(B); 研究期間:2015~2016; 課題番号:15K19079; 研究分野:実験病理; 科研費の分科・細目:Research Paperapplication/pdf

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K19079/

Detailed bibliographic record

Summary, etc.:

研究成果の概要(和文):肺気腫罹患者の多くが喫煙者であるが、禁煙によって進行を止めることは難しい。その分子機序については未解明である。先行研究において、肺気腫では接着分子CADM1の酵素的切断(shedding)が亢進状態にあり、肺胞上皮のアポトーシスを誘導することを明らかにした。本研究では、喫煙誘...

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Digital

Material Type
文書・図像類
Author/Editor
萩山, 満
Author Heading
Publication, Distribution, etc.
Publication Date
2017
Publication Date (W3CDTF)
2017
Alternative Title
Search for drug seeds for treatment of pulmonary emphysema targeting adhesion molecules
Periodical title
科学研究費助成事業研究成果報告書 (2016)
Pages
1-5