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オキサリプラチン誘発性肝類洞閉塞症候群における血液凝固線溶系機構の解明と治療応用

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オキサリプラチン誘発性肝類洞閉塞症候群における血液凝固線溶系機構の解明と治療応用

Material type
文書・図像類
Author
辰巳, 公平ほか
Publisher
近畿大学
Publication date
2018
Material Format
Digital
Capacity, size, etc.
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Notes on use

Note (General):

研究種目:研究活動スタート支援; 研究期間:2016~2017; 課題番号:16H07357; 研究分野:血液学; 科研費の分科・細目:Research Paperapplication/pdf

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H07357/

Detailed bibliographic record

Summary, etc.:

研究成果の概要(和文):オキサリプラチンによる肝類洞閉塞症候群(SOS)の病態形成における凝固線溶因子の関与を明らかにすることを目的とした。薬剤剤投与により肝臓でのPAI-1 発現の増加が見られ、TF 発現は低下した。PAI-1 発現増加と体重減少率には有意な負の相関が見られ、PAI-1増加の病態悪...

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Digital

Material Type
文書・図像類
Author/Editor
辰巳, 公平
梶, 博史
Nigel, Mackman
Publication, Distribution, etc.
Publication Date
2018
Publication Date (W3CDTF)
2018
Alternative Title
The role of blood coagulation and fibrinolysis system in the oxaliplatin-induced liver sinusoidal obstruction syndrome
Periodical title
科学研究費助成事業研究成果報告書 (2017)
Pages
1-6