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driver遺伝子異常肺癌に対する分子標的薬の耐性化と、抗PD1抗体の有効性

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driver遺伝子異常肺癌に対する分子標的薬の耐性化と、抗PD1抗体の有効性

Material type
文書・図像類
Author
林, 秀敏
Publisher
近畿大学
Publication date
2018
Material Format
Digital
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-
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研究種目：若手研究(B); 研究期間：2016～2017; 課題番号：16K21506; 研究分野：臨床腫瘍学; 科研費の分科・細目：Research Paperapplication/pdf

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K21506/

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Summary, etc.：

研究成果の概要（和文）：EGFR-TKIに耐性を示した後にﾆﾎﾞﾙﾏﾌﾞを使用したEGFR変異陽性非小細胞肺がん25例(T790M変異陽性8例)の有効性および免疫関連因子を検討した。陰性症例は陽性と比較して良好な有効性及び、PD-L1が高発現の傾向を示した。ﾆﾎﾞﾙﾏﾌﾞ使用症例9例の全ｴｸｿｰﾑ解...

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Digital

Material Type
文書・図像類
Title
driver遺伝子異常肺癌に対する分子標的薬の耐性化と、抗PD1抗体の有効性
Author/Editor
林, 秀敏
Author Heading
林, 秀敏
Publication, Distribution, etc.
近畿大学
Publication Date
2018
Publication Date (W3CDTF)
2018
Alternative Title
Resistance mechanis of molecular targeted therapy and tumor micro environment as the immune-checkpoint inhibitor's biomarker
Periodical title
科学研究費助成事業研究成果報告書 (2017)
Pages
1-4