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筋萎縮性側索硬化症の原因遺伝子ERBB4を介する発症機序解明と抗がん剤の効果検証

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筋萎縮性側索硬化症の原因遺伝子ERBB4を介する発症機序解明と抗がん剤の効果検証

Material type
文書・図像類
Author
平野, 牧人ほか
Publisher
近畿大学
Publication date
2019
Material Format
Digital
Capacity, size, etc.
-
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Note (General)：

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K09705/研究種目：基盤研究(C); 研究期間：2016～2018; 課題番号：16K09705; 研究分野：臨床神経遺伝学; 科研費の分科・細目：Research Paper...

Detailed bibliographic record

Summary, etc.：

研究成果の概要（和文）：本研究はERBB4を介する筋萎縮性側索硬化症(ALS)発症機序解明と抗がん剤の標的であるリン酸化カスケードを、ALS患者人工多能性幹(iPS)細胞由来神経細胞や神経様培養細胞で検討する事を目的とした。神経系細胞を用いた発現実験の結果、野生型と4種の変異型ERBB4の細胞内分布...

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Digital

Material Type
文書・図像類
Title
筋萎縮性側索硬化症の原因遺伝子ERBB4を介する発症機序解明と抗がん剤の効果検証
Author/Editor
平野, 牧人
西郷, 和真
Author Heading
平野, 牧人
西郷, 和真
Publication, Distribution, etc.
近畿大学
Publication Date
2019
Publication Date (W3CDTF)
2019
Alternative Title
Clarification of pathomechanism via amyotrophic lateral sclerosis-causing ERBB4 and effectiveness of anti-cancer medicine.
Periodical title
科学研究費助成事業研究成果報告書 (2018)
Pages
1-6