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文書・図像類

自己抗原の翻訳後修飾異常を標的としたANCA関連血管炎の早期診断マーカーの開発

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自己抗原の翻訳後修飾異常を標的としたANCA関連血管炎の早期診断マーカーの開発

Material type
文書・図像類
Author
永井, 宏平ほか
Publisher
近畿大学
Publication date
2020
Material Format
Digital
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https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K08998/研究種目:基盤研究(C); 研究期間:2017~2019; 課題番号:17K08998; 研究分野:プロテオミクス; 科研費の分科・細目:Research Paper...

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Summary, etc.:

研究成果の概要(和文):本研究では。ANCA関連血管炎患者の末梢血好中球における、自己抗原Myeloperoxinase(MPO)の翻訳後修飾の解析を行った。ANCA関連血管炎患者8例と健常者8例の末梢血より好中球MPOを精製し、トリプシン消化した後に、高性能のLC-MS で解析した。その結果、MP...

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Digital

Material Type
文書・図像類
Author/Editor
永井, 宏平
加藤, 智啓
黒川, 真奈絵
Publication, Distribution, etc.
Publication Date
2020
Publication Date (W3CDTF)
2020
Alternative Title
Evaluation of alterations in post-translational modification of autoantigens as a novel early phase diagnostic marker for ANCA associated vasculitis.
Periodical title
科学研究費助成事業研究成果報告書 (2019)
Pages
1-4