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文書・図像類

カンナビノイド受容体とT型Caチャネルを標的とする過敏性腸症候群の新規治療戦略

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カンナビノイド受容体とT型Caチャネルを標的とする過敏性腸症候群の新規治療戦略

Material type
文書・図像類
Author
坪田, 真帆
Publisher
近畿大学
Publication date
2021
Material Format
Digital
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Note (General):

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K06710/研究種目:基盤研究(C); 研究期間:2018~2020; 課題番号:18K06710; 研究分野:薬理学; 科研費の分科・細目:Research Paper...

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Summary, etc.:

研究成果の概要(和文):ButyrateおよびTNBS誘起関連痛覚過敏および結腸過敏にCav3.2 T型カルシムチャネルが重要な役割を持つことが明らかになった。一方、CB1およびCB2受容体刺激薬は本モデルにおいて明確な効果を示さなかった。そこで既存医薬品の中でT型カルシムチャネル阻害活性を有する抗...

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  • Kindai University Academic Resource Repository

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Digital

Material Type
文書・図像類
Author/Editor
坪田, 真帆
Author Heading
Publication, Distribution, etc.
Publication Date
2021
Publication Date (W3CDTF)
2021
Alternative Title
New therapeutic strategies for irritable bowel syndrome targeting cannabinoid receptors and T-type calcium channels
Periodical title
科学研究費助成事業研究成果報告書 (2020)
Pages
1-8