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文書・図像類

肝細胞癌におけるチロシンキナーゼ阻害剤の免疫微小環境への影響に関する研究

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肝細胞癌におけるチロシンキナーゼ阻害剤の免疫微小環境への影響に関する研究

Material type
文書・図像類
Author
工藤, 正俊ほか
Publisher
近畿大学
Publication date
2021
Material Format
Digital
Capacity, size, etc.
-
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Notes on use

Note (General):

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K07922/研究種目:基盤研究(C); 研究期間:2018~2020; 課題番号:18K07922; 研究分野:消化器内科; 科研費の分科・細目:Research Paper...

Detailed bibliographic record

Summary, etc.:

研究成果の概要(和文):肝細胞癌(肝癌)において、癌関連シグナルの変化は腫瘍微小免疫環境に影響する可能性がある。本解析により、PD-L1陽性肝癌は腫瘍浸潤リンパ球(TIL)が多く、PI3K-Akt活性型変異が多いことが確認された。一方、β-カテニン経路の活性型変異を持つ肝癌はPD-L1陰性かつTIL...

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Digital

Material Type
文書・図像類
Author/Editor
工藤, 正俊
西田, 直生志
Publication, Distribution, etc.
Publication Date
2021
Publication Date (W3CDTF)
2021
Alternative Title
Effect of tyrosine kinase inhibitor for immunological microenviroment of hepatocellular carcinoma
Periodical title
科学研究費助成事業研究成果報告書 (2020)
Pages
1-16