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新規生活習慣病治療薬開発を目指した遅筋化促進因子過剰発現マウスの作製と機能解析

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新規生活習慣病治療薬開発を目指した遅筋化促進因子過剰発現マウスの作製と機能解析

Material type
文書・図像類
Author
本多, 賢彦
Publisher
近畿大学
Publication date
2021
Material Format
Digital
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Note (General):

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K11486/研究種目:基盤研究(C); 研究期間:2019~2021; 課題番号:19K11486; 研究分野:筋線維タイプ制御; 科研費の分化・細目:Research Paper...

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Summary, etc.:

研究成果の概要(和文):骨格筋は安静時には全身の2割を占めるほどのエネルギー消費を行う。本研究では、筋線維タイプと代謝能力との密接な関係に着目して、遅筋化制御因子であるVgll2の発現レベルが個体の肥満耐性にも影響をおよぼすか、遺伝子改変マウスを用いて検討を行った。まず筋特異的にVgll2を過剰発現...

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Digital

Material Type
文書・図像類
Author/Editor
本多, 賢彦
Author Heading
Publication, Distribution, etc.
Publication Date
2021
Publication Date (W3CDTF)
2021
Alternative Title
Generation and phenotyping of mice overexpressing slow contractile phenotype promoting factor for the development of new metabolic syndrome drugs
Periodical title
科学研究費助成事業研究成果報告書 (2021)
Pages
1-7