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文書・図像類

表皮のNotchシグナルは皮膚免疫を調節するのか?

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表皮のNotchシグナルは皮膚免疫を調節するのか?

Material type
文書・図像類
Author
森山, 麻里子
Publisher
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Publication date
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Material Format
Digital
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Note (General):

研究分野:皮膚科学、分子生物学、細胞生物学

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Summary, etc.:

本研究では、表皮特異的Hes1コンディショナルノックアウト(Hes1cKOepi)マウスを作成し、イミキモドによる乾癬の誘発を行ったところ、当該マウスでは乾癬の特徴的病態の悪化が観察された。さらに、表皮に発現する遺伝子の網羅的解析により、Hes1cKOepiマウスでは表皮ケラチノサイトからの炎症系サ...

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  • Kindai University Academic Resource Repository

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Digital

Material Type
文書・図像類
Author/Editor
森山, 麻里子
Author Heading
Alternative Title
Roles of Notch signaling in the regulation of skin immune system
Periodical title
科学研究費助成事業研究成果報告書 (2022)
Text Language Code
jpn
Target Audience
一般
Note (General)
研究分野:皮膚科学、分子生物学、細胞生物学