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文書・図像類

ビスフォスフォネート製剤関連顎骨壊死の病態機序の解明と,PAI-1の関与についての検討

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ビスフォスフォネート製剤関連顎骨壊死の病態機序の解明と,PAI-1の関与についての検討

Material type
文書・図像類
Author
木下, 優子
Publisher
-
Publication date
-
Material Format
Digital
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研究分野：外科系歯学

Detailed bibliographic record

Summary, etc.：

ビスフォスフォネート(BP)製剤の開発により、骨粗鬆症や悪性腫瘍骨転移の治療成績は向上したが、一方で、重大な副作用として顎骨壊死(BRONJ)が問題になっている。癌患者の長期生存率の向上に伴いBRONJ患者数は増加しているが、そのメカニズムには未だ不明な点が多く、治療方法が確立されておらず根治が難し...

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Digital

Material Type
文書・図像類
Title
ビスフォスフォネート製剤関連顎骨壊死の病態機序の解明と,PAI-1の関与についての検討
Author/Editor
木下, 優子
Author Heading
木下, 優子
Alternative Title
Elucidation of the pathomechanism of bisphosphonate-related osteonecrosis of the jaw and investigation of the involvement
Periodical title
科学研究費助成事業研究成果報告書 (2023)
Text Language Code
jpn
Subject Heading
薬剤関連顎骨壊死
PAI-1
組織線溶系
糖尿病
ビスフォスフォネート製剤
Target Audience
一般
Note (General)
研究分野：外科系歯学