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デスモグレイン3反応性Ｔ細胞の病原性規定因子の同定とその阻害療法の検討

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デスモグレイン3反応性Ｔ細胞の病原性規定因子の同定とその阻害療法の検討

Material type
文書・図像類
Author
高橋, 勇人
Publisher
-
Publication date
2008
Material Format
Digital
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Note (General)：

type:text尋常性天疱瘡(PV)において病態と関連する抗デスモグレイン3(Dsg3)抗体の産生にはDsg3を認識する自己反応性T細胞の関与が推測されている。そこで、PVモデルマウスを利用し、Dsg3反応性T細胞の特性を解析した。まずDsg3反応性T細胞株を樹立し、このT細胞株の中にはPVを誘導...

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科研費研究者番号：40398615

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Digital

Material Type
文書・図像類
Title
デスモグレイン3反応性Ｔ細胞の病原性規定因子の同定とその阻害療法の検討
Author/Editor
高橋, 勇人
Author Heading
高橋, 勇人
Publication Date
2008
Publication Date (W3CDTF)
2008
Alternative Title
デスモグレイン 3 ハンノウセイ Ｔ サイボウ ノ ビョウゲンセイ キテイ インシ ノ ドウテイ ト ソノ ソガイ リョウホウ ノ ケントウ
desumogurein 3 hannosei T saibo no byogensei kitei inshi no dotei to sono sogai ryoho no kento
Identification of pathogenicity determining factors of desmoglein3-reactive T cells and evaluation of its blockade therapy
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
Subject Heading
天疱瘡