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新規ALS原因遺伝子VAPBの機能解析

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新規ALS原因遺伝子VAPBの機能解析

Material type
文書・図像類
Author
金蔵, 孝介
Publisher
-
Publication date
2009
Material Format
Digital
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Note (General)：

type:text新規ALS原因遺伝子VAPBが小胞体ストレス応答シグナル(UPR)に関与することを既に報告してきたが、我々はさらに野生型VAPBが小胞体ストレスセンサーのうち小胞体シャペロンの発現量を上昇させるIRE1経路に対して促進的に、細胞死を誘導するとされるPERK経路に対しては抑制的に働く...

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科研費研究者番号 : 10508568

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Digital

Material Type
文書・図像類
Title
新規ALS原因遺伝子VAPBの機能解析
Author/Editor
金蔵, 孝介
Author Heading
金蔵, 孝介
Publication Date
2009
Publication Date (W3CDTF)
2009
Alternative Title
シンキ ALS ゲンイン イデンシ VAPB ノ キノウ カイセキ
Shinki ALS genin idenshi VAPB no kino kaiseki
Functional analysis of the novel ALS-causative VAPB gene.
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
Subject Heading
ALS,UPR,VAPB,ER stress