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文書・図像類

Aireによる天疱瘡標的抗原に対する免疫寛容機序の解明

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Aireによる天疱瘡標的抗原に対する免疫寛容機序の解明

Material type
文書・図像類
Author
和田, 直子
Publisher
-
Publication date
2010
Material Format
Digital
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Notes on use

Note (General):

type:text転写因子Aireは多くの臓器特異的自己抗原の胸腺内発現を促進し、それらの抗原は自己反応性T細胞の胸腺内除去に寄与することが近年明らかとなった。我々は天疱瘡抗原Dsg3が野生型マウス胸腺髄質上皮細胞にAire依存性に発現すること、Aire非存在下で産生されたT細胞がDsg3-/-マウ...

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科研費研究者番号 : 50306776

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Material Type
文書・図像類
Author/Editor
和田, 直子
Author Heading
Publication Date
2010
Publication Date (W3CDTF)
2010
Alternative Title
Aire ニ ヨル テンポウソウ ヒョウテキ コウゲン ニ タイスル メンエキ カンヨウ キジョ ノ カイメイ
Aire ni yoru tenposo hyoteki kogen ni taisuru meneki kanyo kijo no kaimei
Aire-mediated mechanism of tolerance against Dsg3, the autoantigen in pemphigus vulgaris
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn