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新規EMT誘導因子HOXB9による乳癌悪性化および癌幹細胞群増加メカニズムの検証

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新規EMT誘導因子HOXB9による乳癌悪性化および癌幹細胞群増加メカニズムの検証

Material type
文書・図像類
Author
林田, 哲
Publisher
-
Publication date
2010
Material Format
Digital
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type:text転写因子HOXB9が上皮間質転換(EMT)を誘導することで、癌細胞それ自身の悪性度を高めると同時に、血管新生を通じて腫瘍微小環境を変化させることで、腫瘍増大や転移先における生着を促進していることが確認された。この効果にTGFβ経路の活性化の寄与が重要であることが示されると同時に、臨...

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Digital

Material Type
文書・図像類
Title
新規EMT誘導因子HOXB9による乳癌悪性化および癌幹細胞群増加メカニズムの検証
Author/Editor
林田, 哲
Author Heading
林田, 哲
Publication Date
2010
Publication Date (W3CDTF)
2010
Alternative Title
シンキ EMT ユウドウ インシ HOXB9 ニ ヨル ニュウガン アクセイカ オヨビ ガン カンサイボウグン ゾウカ メカニズム ノ ケンショウ
Shinki EMT yudo inshi HOXB9 ni yoru nyugan akuseika oyobi gan kansaibogun zoka mekanizumu no kensho
HOXB9 promotes the acquisition of tumorigenic phenotypes in breast cancer
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
Subject Heading
乳癌,HOXB9,EMT,予後因子,微小環境,血管新生