文書・図像類

水溶性NF-κB阻害剤のデザイン・合成と卵巣癌の抑制

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水溶性NF-κB阻害剤のデザイン・合成と卵巣癌の抑制

Material type
文書・図像類
Author
梅澤, 一夫ほか
Publisher
-
Publication date
2010
Material Format
Digital
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Notes on use

Note (General):

type:text私たちの見出したDHMEQは特異性が高く、in vivoで有効なNF-κB阻害剤であるが、溶解性が低い。そこで、活性コア以外の部分をかえて、溶解性を向上させた。また、酵素を用いて、医薬開発に必要な光学活性体を効率的に合成できるようにした。一方、DHMEQは培養卵巣癌細胞の浸潤を抑制...

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科研費研究者番号 : 70114402

科研費研究者番号 : 60171120

科研費研究者番号 : 70265875

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Digital

Material Type
文書・図像類
Author/Editor
梅澤, 一夫
須貝, 威
阪埜, 浩司
Publication Date
2010
Publication Date (W3CDTF)
2010
Alternative Title
スイヨウセイ NF-κB ソガイザイ ノ デザイン・ゴウセイ ト ランソウガン ノ ヨクセイ
Suiyosei NF-κB sogaizai no dezain gosei to ransogan no yokusei
Molecular design and synthesis of soluble NF-κB inhibitor and suppression of ovarian carcinoma
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn