文書・図像類

間葉系悪性腫瘍(骨肉腫)の未分化性維持に関わる微小環境の解明

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間葉系悪性腫瘍(骨肉腫)の未分化性維持に関わる微小環境の解明

Material type
文書・図像類
Author
清水, 孝恒
Publisher
-
Publication date
2011
Material Format
Digital
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Notes on use

Note (General)：

type:text我々は新規に樹立した骨肉腫マウスモデルを用いて、非腫瘍細胞(線維芽細胞、マクロファージ)から産生されるFgf2、Lifなど液性因子がErk1/2を強力に活性化し、骨肉腫細胞の未分化維持に関わることを明らかにした。さらにFgf2 は骨肉腫細胞の増殖、遊走を促進し抗癌剤への感受性低下に...

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Material Type
文書・図像類
Title
間葉系悪性腫瘍(骨肉腫)の未分化性維持に関わる微小環境の解明
Author/Editor
清水, 孝恒
Author Heading
清水, 孝恒
Publication Date
2011
Publication Date (W3CDTF)
2011
Alternative Title
カンヨウケイ アクセイ シュヨウ (コツニクシュ) ノ ミブンカセイ イジ ニ カカワル ビショウ カンキョウ ノ カイメイ
Kanyokei akusei shuyo (kotsunikushu) no mibunkasei iji ni kakawaru bisho kankyo no kaimei
Investigation of the roles of tumor environment in osteosarcoma
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
Subject Heading
癌,環境