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ABC輸送体活性・発現制御機構の解明と創薬基盤の構築

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ABC輸送体活性・発現制御機構の解明と創薬基盤の構築

Material type
文書・図像類
Author
片山, 和浩
Publisher
-
Publication date
2012
Material Format
Digital
Capacity, size, etc.
-
NDC
-
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Note (General)：

type:textP-糖タンパク質(P-gp)はABC輸送体に属する抗がん剤排出ポンプである。がん細胞におけるP-gp の発現増加は抗がん剤耐性の一因とされる。本研究では、P-gpの活性や発現の制御方法を調べ、P-gp阻害薬の開発基盤を構築することを目的として遂行した。本研究では、(1) P-gpは...

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科研費研究者番号 : 40406963

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Digital

Material Type
文書・図像類
Title
ABC輸送体活性・発現制御機構の解明と創薬基盤の構築
Author/Editor
片山, 和浩
Author Heading
片山, 和浩
Publication Date
2012
Publication Date (W3CDTF)
2012
Alternative Title
ABC ユソウタイ カッセイ・ハツゲン セイギョ キコウ ノ カイメイ ト ソウヤク キバン ノ コウチク
ABC yusotai kassei hatsugen seigyo kiko no kaimei to soyaku kiban no kochiku
Basic research for development of new drugs based on the regulation of ABC transporters activity and expression
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
Subject Heading
薬物動態・代謝学,ABC輸送体