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リボソーム合成阻害(核小体ストレス)を介した神経膠腫の新たな治療標的分子の開発

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リボソーム合成阻害(核小体ストレス)を介した神経膠腫の新たな治療標的分子の開発

Material type
文書・図像類
Author
三輪, 点
Publisher
-
Publication date
2015
Material Format
Digital
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Note (General):

type:text各種神経膠腫細胞株・神経膠腫患者組織・脳腫瘍幹細胞株・他の癌腫細胞株におけるEFTUD1の発現解析を行った結果gliomaにおいてEFTUD1の発現がみられる一方で, 正常脳組織では発現は見られなかった。機能解析ではEFTUD1を特異的にknock downすることでglioma ...

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科研費研究者番号 : 20365282

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  • Keio Associated Repository of Academic resources

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Digital

Material Type
文書・図像類
Author/Editor
三輪, 点
Author Heading
Publication Date
2015
Publication Date (W3CDTF)
2015
Alternative Title
リボソーム ゴウセイ ソガイ (カクショウタイ ストレス) オ カイシタ シンケイ コウシュ ノ アラタナ チリョウ ヒョウテキ ブンシ ノ カイハツ
Ribosomu gosei sogai (kakushotai sutoresu) o kaishita shinkei koshu no aratana chiryo hyoteki bunshi no kaihatsu
Development of a new molecular target for glioma mediated ribosome synthesis inhibition (nucleolar stress)
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
eng
Subject Heading