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遺伝子改変オルガノイドを用いたヒト大腸がん遺伝子の機能的解析基盤の構築

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遺伝子改変オルガノイドを用いたヒト大腸がん遺伝子の機能的解析基盤の構築

Material type
文書・図像類
Author
佐藤, 俊朗
Publisher
-
Publication date
2016
Material Format
Digital
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type:text近年の次世代シークエンス技術の進歩と大規模なシークエンス解析プロジェクトにより, 大腸がんの網羅的ながん遺伝子変異同定が可能になった。我々は, 大腸上皮組織の体外培養技術であるオルガノイド培養とCRISPR-Cas9ゲノム編集技術を組み合わせ, ヒト大腸上皮遺伝子変異導入オルガノイ...

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Digital

Material Type
文書・図像類
Title
遺伝子改変オルガノイドを用いたヒト大腸がん遺伝子の機能的解析基盤の構築
Author/Editor
佐藤, 俊朗
Author Heading
佐藤, 俊朗
Publication Date
2016
Publication Date (W3CDTF)
2016
Alternative Title
イデンシ カイヘン オルガノイド オ モチイタ ヒト ダイチョウガン イデンシ ノ キノウテキ カイセキ キバン ノ コウチク
Idenshi kaihen oruganoido o mochiita hito daichogan idenshi no kinoteki kaiseki kiban no kochiku
Establishment of gene engineered organoids for functional analysis of human colorectal driver gene mutations
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
eng
Subject Heading
大腸癌,浸潤,転移,オルガノイド,幹細胞