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セツキシマブ耐性口腔扁平上皮癌幹細胞を標的とした治療法の開発

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セツキシマブ耐性口腔扁平上皮癌幹細胞を標的とした治療法の開発

Material type
文書・図像類
Author
吉川, 桃子
Publisher
-
Publication date
2016
Material Format
Digital
Capacity, size, etc.
-
NDC
-
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Notes on use

Note (General)：

type:text癌幹細胞マーカーであるCD44v陽性口腔扁平上皮癌細胞を用いて, EGFR標的治療薬セツキシマブに耐性を有する細胞を作製し, 耐性化に伴う癌幹細胞の性質の変化を解析した。セツキシマブ耐性細胞では親株に比べてCD44v陽性の未分化な腫瘍を形成する細胞と遺伝子発現が類似しており, 実際...

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科研費研究者番号 : 50570967

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Digital

Material Type
文書・図像類
Title
セツキシマブ耐性口腔扁平上皮癌幹細胞を標的とした治療法の開発
Author/Editor
吉川, 桃子
Author Heading
吉川, 桃子
Publication Date
2016
Publication Date (W3CDTF)
2016
Alternative Title
セツキシマブ タイセイ コウクウ ヘンペイ ジョウヒガン カンサイボウ オ ヒョウテキ ト シタ チリョウホウ ノ カイハツ
Setsukishimabu taisei koku henpei johigan kansaibo o hyoteki to shita chiryoho no kaihatsu
Development of the therapy for cetuximab-resistant oral squamous cell carcinoma cells
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
eng
Subject Heading
CD44v,口腔扁平上皮癌,セツキシマブ