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ヒトiPS細胞を用いた遺伝性進行性難聴DFNA5の病態解析と創薬スクリーニング

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ヒトiPS細胞を用いた遺伝性進行性難聴DFNA5の病態解析と創薬スクリーニング

Material type
文書・図像類
Author
細谷, 誠
Publisher
-
Publication date
2020
Material Format
Digital
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type:text健聴者由来iPS細胞に対してDFNA5遺伝子変異をCRISPR/Cas9システムを用いて導入し、DFNA5変異ヒトiPS細胞を作成した。DFNA5は難聴遺伝子として知られており、本遺伝子によって生じる難聴のメカニズムの解明を目指して、本iPS細胞より内耳細胞を誘導し正常iPS由来内...

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科研費研究者番号 : 30645445

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Digital

Material Type
文書・図像類
Title
ヒトiPS細胞を用いた遺伝性進行性難聴DFNA5の病態解析と創薬スクリーニング
Author/Editor
細谷, 誠
Author Heading
細谷, 誠
Publication Date
2020
Publication Date (W3CDTF)
2020
Alternative Title
ヒト iPS サイボウ オ モチイタ イデンセイ シンコウセイ ナンチョウ DFNA5 ノ ビョウタイ カイセキ ト ソウヤク スクリーニング
Hito iPS saibō o mochiita idensei shinkōsei nanchō DFNA5 no byōtai kaiseki to sōyaku sukurīningu
Pathological analysis and drug screening of hereditary progressive deafness DFNA5 using human iPS cells
Periodical title
科学研究費補助金研究成果報告書
Text Language Code
jpn
eng
Subject Heading
遺伝性難聴