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血球細胞DNAメチル化プロファイルに基づくエピゲノム年齢と腎臓DNA損傷との関連

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血球細胞DNAメチル化プロファイルに基づくエピゲノム年齢と腎臓DNA損傷との関連

Material type
文書・図像類
Author
林, 香
Publisher
慶應義塾大学
Publication date
2021
Material Format
Digital
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Note (General):

type:text申請者はこれまで、DNAメチル化やヒストン修飾などのエピゲノム変化の腎臓病病態への影響に注目して検討し報告してきた(JCI 2014, Kidney Int 2015)。また最近ではDNA損傷修復がエピゲノム変化形成の原因の一つであることを、糖尿病性腎症モデルを用いて明らかにした(...

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Digital

Material Type
文書・図像類
Author/Editor
林, 香
Author Heading
Publication, Distribution, etc.
Publication Date
2021
Publication Date (W3CDTF)
2021
Alternative Title
ケッキュウ サイボウ DNA メチルカ プロファイル ニ モトズク エピゲノム ネンレイ ト ジンゾウ DNA ソンショウ トノ カンレン
Kekkyū saibō DNA mechiruka purofairu ni motozuku epigenomu nenrei to jinzō DNA sonshō tono kanren
Association of kidney DNA damage with the 'epigenetic age' based on DNA methylation profiles of blood cells
Periodical title
学事振興資金研究成果実績報告書
Text Language Code
jpn
eng