神経膠腫におけるMRIテクスチャー解析及び髄液DNAによる術前分子診断の探索

Material type: 文書・図像類

Author: 笹尾, 亮太

Publisher: -

Publication date: 2021

Material Format: Digital

Capacity, size, etc.: -

NDC: -

View All

Notes on use

Note (General)：: type:textMazdaによる解析では diffusion weighted imageのHorzl_Fraction、135dr_shrtREMpの併用で陽性的中率90％、感度42.9％で予想可能で、SYNAPSE VINCENTによる解析ではAppearent diffusion coeff...

Related materials as well as pre- and post-revision versions

科研費研究者番号 : 60837201

Search by Bookstore

Holdings of Libraries in Japan

This page shows libraries in Japan other than the National Diet Library that hold the material.

List of Cooperating Institutions and Databases

Please contact your local library for information on how to use materials or whether it is possible to request materials from the holding libraries.

other

Keio Associated Repository of Academic resources
Digital
You can check the holdings of institutions and databases with which Institutional Repositories DataBase(IRDB)(Institutional Repository) is linked at the site of Institutional Repositories DataBase(IRDB)(Institutional Repository).
Keio Associated Repository of Academic resources

Search by Bookstore

Bibliographic Record

You can check the details of this material, its authority (keywords that refer to materials on the same subject, author's name, etc.), etc.

Digital

Material Type: 文書・図像類
Title: 神経膠腫におけるMRIテクスチャー解析及び髄液DNAによる術前分子診断の探索
Author/Editor: 笹尾, 亮太
Author Heading: 笹尾, 亮太
Publication Date: 2021
Publication Date (W3CDTF): 2021
Alternative Title: シンケイコウシュニオケル MRI テクスチャーカイセキオヨビズイエキ DNA ニヨルジュツゼンブンシシンダンノタンサク
Shinkei kōshu ni okeru MRI tekusuchā kaiseki oyobi zuieki DNA ni yoru jutsuzen bunshi shindan no tansaku
Using MRI texture analysis and cerebrospinal DNA fluid in glioblastoma for preoperative molecular diagnostics
Periodical title: 科学研究費補助金研究成果報告書
Text Language Code: jpn
eng
Subject Heading: 膠芽腫,MRIテクスチャー解析,髄液DNA,術前分子診断
Target Audience: 一般
Note (General): type:text
Mazdaによる解析では diffusion weighted imageのHorzl_Fraction、135dr_shrtREMpの併用で陽性的中率90％、感度42.9％で予想可能で、SYNAPSE VINCENTによる解析ではAppearent diffusion coefficienntのmean ADC valueと ADCentrophyの併用で、陽性的中率81.2%、感度61.9%での予測が可能であった。 liquid biopsyによる神経膠腫分子診断は、倫理面から腰椎穿刺での採取は難しく、適切な症例が十分に確保できなかった。 In the analysis by Mazda, it was predictable with a positive predictive value of 90% and a sensitivity of 42.9% when the diffusion weighted image Horzl_Fraction and 135dr_shrtREMp were used together. In the analysis by SYNAPSE VINCENT, it was possible to predict with a positive predictive value of 81.2% and a sensitivity of 61.9% by using the mean ADC value of Appearent diffusion coefficiennt and the ADC entrophy together. Molecular diagnosis of glioma by liquid biopsy was difficult to collect by lumbar puncture from the ethical point of view, and it was not possible to secure sufficient appropriate cases.
研究種目 : 若手研究研究期間 : 2019～2021 課題番号 : 19K18405 研究分野 : 脳腫瘍
Access Restrictions: 限定公開
Related Material: 科研費研究者番号 : 60837201
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 慶應義塾大学 : 慶應義塾大学学術情報リポジトリ