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核膜内膜蛋白Man1による心臓の左右非対称性制御メカニズム

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核膜内膜蛋白Man1による心臓の左右非対称性制御メカニズム

Material type
文書・図像類
Author
石村, 昭彦ほか
Publisher
金沢大学がん進展制御研究所
Publication date
2009-05-26
Material Format
Digital
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Notes on use

Note (General):

Man1は核膜内膜に局在する蛋白質である。本研究ではMan1欠損マウスを作製し、その異常を観察した結果、欠損マウスは心奇形を高頻度に発症し、妊娠中期に死亡した。この心奇形は、心臓発生に必須な左右軸形成メカニズムの異常、つまりNodalシグナル制御の異常に起因した。以上の研究成果は、Developme...

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/search/?qm=80375261

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790147/

https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790147/19790147seika/

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  • Kanazawa University Repository for Academic Resources

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Digital

Material Type
文書・図像類
Author/Editor
石村, 昭彦
Ishimura, Akihiko
Publication, Distribution, etc.
Publication Date
2009-05-26
Publication Date (W3CDTF)
2009-05-26
Alternative Title
A role of Man1, an inner nuclear membrane protein, in left-right axis formation
Periodical title
平成20(2008)年度 科学研究費補助金 若手研究(B) 研究成果報告書 = 2008 Fiscal Year Final Research Report
No. or year of volume/issue
2007-2008