乳癌術後の上肢リンパ浮腫患者に対する皮膚硬さの変化と真皮層および脂肪層の変化

Material type: 文書・図像類

Author: 壺, 美佐子ほか

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Publication date: 2015-05-29

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Note (General)：: 金沢大学医薬保健研究域保健学系乳癌術後のリンパ浮腫患者に対し、徒手的リンパドレナージ（MLD)直前直後の真皮・皮下組織構造変化を超音波診断画像解析より明らかにした。横断観察研究で、15名（30肢）を対象とし国内3施設で調査した。皮膚硬さの主観評価を評定し、MLD直後に柔らかくなった者と変わらなかった...

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https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25862142/25862142seika/

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Material Type: 文書・図像類
Title: 乳癌術後の上肢リンパ浮腫患者に対する皮膚硬さの変化と真皮層および脂肪層の変化
Author/Editor: 壺, 美佐子
Dai, Misako
Author Heading: 壺, 美佐子
Dai, Misako
Publication Date: 2015-05-29
Publication Date (W3CDTF): 2015-05-29
Alternative Title: Skin hardness and imaging of the skin and subcutaneous tissue on ultrasonography before and immediately after lymph drainage
Periodical title: 平成26(2014)年度科学研究費補助金若手研究(B) 研究成果報告書 = 2014 Fiscal Year Final Research Report
No. or year of volume/issue: 2013-04-01 - 2015-03-31
Volume: 2013-04-01 - 2015-03-31
Pages: 4p.-
Text Language Code: jpn
Subject Heading: リンパ浮腫
超音波診断画像
リンパドレナージ
治療効果評価
浮腫減少
Target Audience: 一般
Note (General): 金沢大学医薬保健研究域保健学系
乳癌術後のリンパ浮腫患者に対し、徒手的リンパドレナージ（MLD)直前直後の真皮・皮下組織構造変化を超音波診断画像解析より明らかにした。横断観察研究で、15名（30肢）を対象とし国内3施設で調査した。皮膚硬さの主観評価を評定し、MLD直後に柔らかくなった者と変わらなかった者と比較した。真皮の低輝度所見割合(LEP）と皮下組織の不均一度Pixel uniformityが皮膚の柔らかくなった群で統計学的有意に減少を示した。MLD直前直後の微量な変化を超音波診断画像のLEPとPixel uniformityで評価可能であることが示唆された。
I revealed the changes structure in skin and subcutaneous tissue on ultrasonography(US) before and immediately after manual lymph drainage (MLD) in breast cancer-related lymphedema patients (BCRL).This observational study examined 30 limbs with unilateral secondary lymphedema attending three lymphedema clinics in Japan. Skin hardness was assessed using a 10-cm visual analog scale (VAS). US was performed at 20 MHz for skin and 10 MHz for subcutaneous tissue. Patients were assigned to Group A (n=10) with decreased VAS and Group B (n=5) with unchanged VAS. Results of US and other characteristics were then compared between groups. Group A showed decreased numbers of low-echogenic pixels (LEP) and decreased pixel uniformity after MLD, whereas Group B did not. These findings suggest that interstitial fluid in the dermis and subcutaneous tissue is decreased after MLD in BCRL who report softening of the skin, and can therefore be used as a quantitative indicator for the effectiveness of MLD.
研究課題/領域番号:25862142, 研究期間(年度):2013-04-01 - 2015-03-31
DOI: 10.24517/00051202
Access Restrictions: 限定公開
Related Material: https://kaken.nii.ac.jp/search/?qm=50614864
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25862142/
https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25862142/25862142seika/
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 金沢大学 : 金沢大学学術情報リポジトリKURA