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白金錯体の非共有性相互作用に基づく抗がん活性解明と創薬化

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白金錯体の非共有性相互作用に基づく抗がん活性解明と創薬化

Material type
文書・図像類
Author
小谷, 明ほか
Publisher
-
Publication date
2017-06-08
Material Format
Digital
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Note (General)：

金沢大学医薬保健研究域薬学系芳香環スタッキングを有する混合配位子白金錯体が臨床白金抗がん剤シスプラチンよりも高い抗がん活性，低い副作用を示した．リン酸基と白金配位アミン間の水素結合は骨へのデリバリー，低副作用化に有用であり，金属ポルフィリンと組み合わされた白金錯体は光により活性化され高いin viv...

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https://kaken.nii.ac.jp/search/?qm=60143913

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25288027/

https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25288027/25288027seika/

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Digital

Material Type
文書・図像類
Title
白金錯体の非共有性相互作用に基づく抗がん活性解明と創薬化
Author/Editor
小谷, 明
Odani, Akira
Author Heading
小谷, 明
Odani, Akira
Publication Date
2017-06-08
Publication Date (W3CDTF)
2017-06-08
Alternative Title
Study of anticancer Pt complexes involving with non-covalent interactions and its application for drug
Periodical title
平成28(2016)年度 科学研究費補助金 基盤研究(B) 研究成果報告書 = 2016 Fiscal Year Final Research Report
No. or year of volume/issue
2013-04-01 - 2017-03-31
Volume
2013-04-01 - 2017-03-31