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フォークヘッド転写因子Foxoによる白血病幹細胞の維持機構の解明

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フォークヘッド転写因子Foxoによる白血病幹細胞の維持機構の解明

Material type
文書・図像類
Author
仲, 一仁ほか
Publisher
金沢大学がん研究所
Publication date
2011-03-31
Material Format
Digital
Capacity, size, etc.
-
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ヒト慢性骨髄性白血病(Chronic myeloid leukemia;CML)の治療にはチロシンキナーゼ阻害剤イマチニブが広く用いられているが,イマチニブ抵抗性の白血病幹細胞の残存はCMLの再発を引き起す原因となる.本研究では,CMLマウスモデルより純化した白血病幹細胞を用いて,TGF-・-FOX...

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https://kaken.nii.ac.jp/search/?qm=70372688

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20590394/

https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20590394/20590394seika/

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  • Kanazawa University Repository for Academic Resources

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Digital

Material Type
文書・図像類
Title
フォークヘッド転写因子Foxoによる白血病幹細胞の維持機構の解明
Author/Editor
仲, 一仁
Naka, Kazuhito
Author Heading
仲, 一仁
Naka, Kazuhito
Publication, Distribution, etc.
金沢大学がん研究所
Publication Date
2011-03-31
Publication Date (W3CDTF)
2011-03-31
Alternative Title
Molecular mechanisms maintaining leukemic stem cells by forkhead transcription factor Foxo
Periodical title
平成22(2010)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 = 2010 Fiscal Year Final Research Report
No. or year of volume/issue
2008-2010