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皮膚硬化型慢性GVHDマウスにおける選択的SIP1阻害剤の有効性の検討

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皮膚硬化型慢性GVHDマウスにおける選択的SIP1阻害剤の有効性の検討

Material type
文書・図像類
Author
加納, 美優ほか
Publisher
-
Publication date
2018-06-27
Material Format
Digital
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金沢大学附属病院スフィンゴシン-１-リン酸（S1P）/S1P受容体シグナルは免疫担当細胞の分化・遊走を制御しており、全身性強皮症において重要な治療標的である。新規選択的S1P1受容体阻害剤を皮膚硬化型慢性GVHDモデルマウスに投与したところ、皮膚及び肺の線維化は改善し皮膚への炎症細胞浸潤は減少した。...

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/ja/search/?kw=60756237

https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-16K19713/

https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-16K19713/16K19713seika/

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Digital

Material Type
文書・図像類
Title
皮膚硬化型慢性GVHDマウスにおける選択的SIP1阻害剤の有効性の検討
Author/Editor
加納, 美優
Kano, Miyu
Author Heading
加納, 美優
Kano, Miyu
Publication Date
2018-06-27
Publication Date (W3CDTF)
2018-06-27
Alternative Title
The selective S1P1 modulator ameliorates murine Sclerodermatous Chronic Graft Versus Host Disease
Periodical title
平成29(2017)年度 科学研究費補助金 若手研究(B) 研究成果報告書 = 2017 Fiscal Year Final Research Report
No. or year of volume/issue
2016-04-01 – 2018-03-31
Volume
2016-04-01 – 2018-03-31