顎関節症滑膜炎誘導機構の解明

Material type: 文書・図像類

Author: 小林, 一彦ほか

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Publication date: 2020-05-11

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Note (General)：: 金沢大学附属病院歯科口腔外科本研究は以下の3研究項目のもとに、in vivoでのエラスチン断片やIL-6による顎関節滑膜炎の誘導メカニズムを検証した。１；in vivoでのエラスチン断片による顎関節でのIL-6の産生誘導と顎関節OA様変化の観察　２；関節症自然発症マウスを用いた顎関節症の検証　３；腱...

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Material Type: 文書・図像類
Title: 顎関節症滑膜炎誘導機構の解明
Author/Editor: 小林, 一彦
Kobayashi, Kazuhiko
Author Heading: 小林, 一彦
Kobayashi, Kazuhiko
Publication Date: 2020-05-11
Publication Date (W3CDTF): 2020-05-11
Alternative Title: Analysis of the mechanism for inducing temporomandibular synovitis
Periodical title: 令和1(2019)年度科学研究費補助金若手研究研究成果報告書 = 2019 Fiscal Year Final Research Report
No. or year of volume/issue: 2018-04-01 - 2020-03-31
Volume: 2018-04-01 - 2020-03-31
Pages: 4p.-
Text Language Code: jpn
Subject Heading: 顎関節症
滑膜炎
エラスチン
Basic Section 57060:Surgical dentistry-related
Target Audience: 一般
Note (General): 金沢大学附属病院歯科口腔外科
本研究は以下の3研究項目のもとに、in vivoでのエラスチン断片やIL-6による顎関節滑膜炎の誘導メカニズムを検証した。１；in vivoでのエラスチン断片による顎関節でのIL-6の産生誘導と顎関節OA様変化の観察　２；関節症自然発症マウスを用いた顎関節症の検証　３；腱、靭帯組織でIL-6を発現する遺伝子改変マウスでの顎関節病変の観察
This study verified the inducing mechanism of temporomandibular joint synovitis by elastin fragments and IL-6 in in vivo under the following three study items. 1; Induced production of IL-6 in the temporomandibular joint by elastin fragments at in vivo and observed temporomandibular joint OA-like changes. 2; Validation of temporomandibular disorders using spontaneous arthropathic mice. 3; Observations on Temporomandibular Joint Lesions in Genetically Modified Mice Expressing IL-6 in Tendons and Ligament Tissues.
研究課題/領域番号:18K17166, 研究期間(年度):2018-04-01 - 2020-03-31
出典：「顎関節症滑膜炎誘導機構の解明」研究成果報告書　課題番号18K17166（KAKEN：科学研究費助成事業データベース（国立情報学研究所））（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K17166/18K17166seika/)を加工して作成
DOI: 10.24517/00057825
Access Restrictions: 限定公開
Related Material: https://kaken.nii.ac.jp/search/?qm=60802832
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K17166/
https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K17166/18K17166seika/
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 金沢大学 : 金沢大学学術情報リポジトリKURA