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個別化薬物療法最適化の基盤となる薬物代謝酵素活性を評価する核医学画像診断法の確立

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個別化薬物療法最適化の基盤となる薬物代謝酵素活性を評価する核医学画像診断法の確立

Material type
文書・図像類
Author
川井, 惠一ほか
Publisher
金沢大学医薬保健研究域保健学系
Publication date
2021-05-31
Material Format
Digital
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Note (General)：

精神疾患の薬物療法に共通した薬効・副作用の個体差要因であるcytochrome P450(CYP)に注目し、多くの向精神薬の代謝に関与するCYP2D6活性測定に適した新規放射性画像診断薬の開発を試みた。CYP2D6の基質である抗ヒスタミン薬のｍequitazineを標識母体化合物に選択し、p-ヨード...

Related materials as well as pre- and post-revision versions

https://kaken.nii.ac.jp/search/?qm=30204663

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K19508/

https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K19508/18K19508seika/

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Digital

Material Type
文書・図像類
Title
個別化薬物療法最適化の基盤となる薬物代謝酵素活性を評価する核医学画像診断法の確立
Author/Editor
川井, 惠一
Kawai, Keiichi
Author Heading
川井, 惠一
Kawai, Keiichi
Publication, Distribution, etc.
金沢大学医薬保健研究域保健学系
Publication Date
2021-05-31
Publication Date (W3CDTF)
2021-05-31
Alternative Title
Establishment of Nuclear Medicine Diagnostic Method to Evaluate Drug Metabolizing Enzyme Activity for Personalized Pharmacotherapy Optimization
Periodical title
令和2(2020)年度 科学研究費補助金 挑戦的研究(萌芽) 研究成果報告書 = 2020 Fiscal Year Final Research Report
No. or year of volume/issue
2018-06-29 - 2021-03-31