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細胞内オルガネラ膜トランスポーター活性の定量的可視化による薬物の細胞毒性評価

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細胞内オルガネラ膜トランスポーター活性の定量的可視化による薬物の細胞毒性評価

Material type
文書・図像類
Author
玉井, 郁己ほか
Publisher
-
Publication date
2016-04-21
Material Format
Digital
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金沢大学薬学系本研究では細胞内での医薬品動態を解析するために、蛍光プローブを用いた可視化によるin vitro評価系の樹立を試みた。医薬品の多くは胆汁中に排泄されるがその過程には肝胆管腔側細胞膜に複数のABCトランスポーターが介在する。医薬品ならびにその抱合代謝物の胆汁中排泄にはMRP2(ABCC2...

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Material Type
文書・図像類
Title
細胞内オルガネラ膜トランスポーター活性の定量的可視化による薬物の細胞毒性評価
Author/Editor
玉井, 郁己
Tamai, Ikumi
Author Heading
玉井, 郁己
Tamai, Ikumi
Publication Date
2016-04-21
Publication Date (W3CDTF)
2016-04-21
Periodical title
平成22(2010)年度 科学研究費補助金 挑戦的萌芽研究 研究課題概要 = 2010 Research Project Sumary
No. or year of volume/issue
2009 – 2010
Volume
2009 – 2010
Pages
4p.-