Fasudil, a Rho kinase inhibitor, suppresses tumor growth by inducing CXCL14/BRAK in head and neck squamous cell carcinoma

• Material Type: 博士論文
• Title: Fasudil, a Rho kinase inhibitor, suppresses tumor growth by inducing CXCL14/BRAK in head and neck squamous cell carcinoma
• Author/Editor: 本橋, 一彦; Motohashi, Kazuhiko
• Author Heading: 本橋, 一彦 モトハシ, カズヒコ; Motohashi, Kazuhiko
• Alternative Title: Rhoキナーゼ阻害剤ファスジルは，CXCL14/BRAKの誘導を介して口腔扁平上癌の進展を抑制する
• Degree Grantor: 神奈川歯科大学
• Date Granted: 2015-03-17
• Dissertation Number: 甲第457号
• Degree Type: 博士（歯学）
• Text Language Code: eng
• Subject Heading: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Chemokines, CXC; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Protein Kinase Inhibitors; RNA, Messenger; Real-Time Polymerase Chain Reaction; rho-Associated Kinases
• Target Audience: 一般
• Note (General): 出版タイプ： VoR; 2014; application/pdf
• Format (IMT): application/pdf
• Source: Full Text（全文） （fulltext）; https://kdu.repo.nii.ac.jp/record/25/files/kou457_fulltext.pdf
• Access Restrictions: インターネット公開
• Rights (production): CC BY-NC-ND
• Related Material: Biomedical Research, 35(6):381-388, 2014. doi: 10.2220/biomedres.35.381; J-STAGE; https://www.jstage.jst.go.jp/article/biomedres/35/6/35_381/_article
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 神奈川歯科大学 : 神奈川歯科大学リポジトリ

• Summary, etc.: CXCL14/BRAK (BRAK) is a secreted chemokine with anti-tumor activity, and its expression is suppressed in tumor cells. We previously reported the anti-...