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- Material Type
- 文書・図像類
- Author/Editor
- 松永, 明
- Author Heading
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- Alternative Title
- Usefulness of volatile biomarkers in breath for perioperative management
- Text Language Code
- jpn
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- Target Audience
- 一般
- Note (General)
- 2012-2013年度科学研究費助成事業（挑戦的萌芽研究）研究成果報告書 課題番号：24659700 研究代表者：松永明（鹿児島大学・医歯（薬）学総合研究科・准教授）本研究は、周術期の患者管理に有用な呼気ガス中の揮発性有機化合物（volatile Organic Compounds: VOCs）を特定し、そのガスセンサを開発することである。ガスクロマトグラフィーを用いて侵襲度の高い手術における呼気ガス中VOCsの変動を測定したが、有用なマーカーを特定できなかった。VOCs測定のためのガスセンサは、水蒸気の影響や触媒活性の低下などがその測定精度に影響を与えることが分かった。The aim of this study was to identify the useful volatile organic compounds (VOCs) in breath for evaluating perioperative patients, and to develop the accurate gas sensor for measuring the concentration of the VOCs. Changes in VOCs in breath were analyzed by gas chromatography in patients who underwent highly invasive operations. However, the useful volatile biomarkers were not identified. Water vapor content and lowing catalytic activity decreased the accuracy of gas sensor for measuring VOCs.