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- Material Type
- 文書・図像類
- Author/Editor
- 宮脇, 正一
- Author Heading
- Publication, Distribution, etc.
- Alternative Title
- Influence of gastric motility on sleep bruxism
- Text Language Code
- jpn
- Target Audience
- 一般
- Note (General)
- 2010-2011年度科学研究費助成事業(科学研究費補助金(挑戦的萌芽研究))研究成果報告書 課題番号：22659377 研究代表者：宮脇正一 (鹿児島大学大学院医歯学総合研究科教授)「胃の蠕動機能が咀嚼様運動を示すブラキシズムと密接に関連する」とする仮説に基づき、胃の運動機能と咀嚼との関連を^{13}C呼気試験によって実験的に検討した。咀嚼するとTmax、Tlag、T_{1/2}は有意に遅延し、胃電図のドミナントパワーは摂食後、一過性に低下した後、持続的に上昇した。即ち、咀嚼で胃の活動は一過性に抑制され、食物排出は一時的に抑制された後、持続的に亢進することがわかった。つまり、胃の蠕動機能は咀嚼様運動を示すブラキシズムと関連する可能性が示唆された。Based on the hypothesis that gastric motility is related with bruxism that shows mastication-like movement, we conducted a randomized trial to compare the effects of mastication on gastric emptying and gastric myoelectrical activity under conditions that excluded the influences of food comminution, taste, and olfaction using ^{13}C-acetate breath test in 14 healthy men who ingested a test meal with or without chewing gum. Gastric emptying was significantly delayed in the ingestion. Gastric myoelectrical activity was significantly suppressed during mastication and increased gradually in the post-mastication phase. A decrease in the high-frequency power of heart rate variability occurred coincidentally with gastric myoelectrical activity suppression. These findings suggest that initial gastric emptying is suppressed by mastication and that the suppression is caused by mastication-induced inhibition of gastric activity and a possibility that gastric motility is closely related with bruxism.