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- Material Type
- 文書・図像類
- Author/Editor
- 郡山, 千早
- Author Heading
- Publication, Distribution, etc.
- Alternative Title
- The roles of unsaturated fatty acids in breast cancer risk and the responsiveness to treatment
- Text Language Code
- jpn
- Target Audience
- 一般
- Note (General)
- 2008-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号：20590650 研究代表者：郡山千早 (鹿児島大学大学院医歯学総合研究科・准教授)本研究では、乳がん症例とがん検診目的で受診した対照群を用いて、年齢、肥満度、およびその他の生活習慣・出産歴等の分布を考慮しながら、血清中のn-3系高度不飽和脂肪酸と乳がんリスクとの関連を検討した。症例群と対照群では、血清中のアラキドン酸/EPA比、アラキドン酸/DHA比のいずれにおいても両群間に有意な差は認めなかった。また乳がん患者の抑うつ状態とアラキドン酸/DHA比との間に弱い正の相関傾向があった。In the present study, the association between n-3 highly-unsaturated fatty acids in serum and the breast cancer risk was examined in taking account the risk factors of breast cancer such as age, obesity, reproductive history and other life styles. There was no significant difference in the ratios of arachidonic acid to EPA and DHA in blood serum between breast cancer case and control groups. There was a weakly-positive association between the ratio of arachidonic acid to DHA and depressive state in breast cancer patients.