流体力学解析を用いた閉塞性睡眠時無呼吸の上気道通気状態に対する口腔内装置の治療効果に関する研究

• Material Type: 博士論文
• Title: 流体力学解析を用いた閉塞性睡眠時無呼吸の上気道通気状態に対する口腔内装置の治療効果に関する研究
• Author/Editor: 菅, 北斗
• Author Heading: 菅, 北斗 スガ, ホクト
• Publication, Distribution, etc.: Taylor & Francis Group
• Publication Date: 2019
• Publication Date (W3CDTF): 2019
• Alternative Title: Evaluation of the effect of oral appliance treatment on upper-airway ventilation conditions in obstructive sleep apnea using computational fluid dynamics
• Periodical title: THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE
• Degree grantor/type: 鹿児島大学
• Date Granted: 2019-09-17
• Dissertation Number: 乙総論第38号
• Degree Type: 博士(歯学); Doctor of Philosophy in Dental Science
• Text Language Code: eng
• Subject Heading: Airway obstruction; computational fluid dynamics; computed tomography; obstructive; oral appliance; polysomnography; respiration; sleep apnea
• Target Audience: 一般
• Note (General): 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Objective: To evaluate the effect of oral appliance (OA) treatment on upper-airway ventilation conditions in patients with obstructive sleep apnea (OSA) using computational fluid dynamics (CFD). Methods: Fifteen patients received OA treatment and underwent polysomnography (PSG) and computed tomography (CT). CT data were used to reconstruct three-dimensional models of nasal and pharyngeal airways. Airflow velocity and airway pressure measurements at inspiration were simulated using CFD. Results: The apnea–hypopnea index (AHI) improved from 23.1 to 10.1 events/h after OA treatment. On CFD analysis, airflow velocity decreased at the retropalatal and epiglottis-tip levels, while airway pressure decreased at the retropalatal, uvular- and epiglottis-tip levels. The AHI of patients with OSA before OA treatment was correlated with airway pressure at the epiglottis-tip level. Discussion: Treatment with OA improved the ventilation conditions of the pharyngeal airway and AHI. Results of CFD analysis of airway pressure and airflow velocity helped determine the severity and ventilatory impairment site of OSA, respectively. Hokuto Suga, Tomonori Iwasaki, Katsuaki Mishima, Hiroyuki Nakano, Yoshiya Ueyama and Youichi Yamasaki Evaluation of the effect of oral appliance treatment on upper-airway ventilation conditions in obstructive sleep apnea using computational fluid dynamics CRANIO®: THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE 2019 https://doi.org/10.1080/08869634.2019.1596554
• Format (IMT): application/pdf
• Access Restrictions: インターネット公開
• Related Material (DOI): 10.1080/08869634.2019.1596554
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 鹿児島大学 : 鹿児島大学リポジトリ

Table of Contents

Result_Suga_Hokuto_isk_38 other

Comments_Suga_Hokuto_isk_38 other

Diss_菅_北斗_ISKr38_2019 fulltext

Abstract_菅_北斗_TO_2019 abstract