大学生を対象とした Working Memory に関連する前頭前野脳血流反応の研究 : 主観的ウェルビーングと生活習慣との相関研究

• Material Type: 博士論文
• Title: 大学生を対象とした Working Memory に関連する前頭前野脳血流反応の研究 : 主観的ウェルビーングと生活習慣との相関研究
• Author/Editor: 川池, 陽一
• Publication, Distribution, etc.: 鹿児島大学
• Alternative Title: Working Memory-Related Prefrontal Hemodynamic Responses in University Students : A Corralation Study of Subjective Well-Being and Lifestyle Habits
• Degree grantor/type: 鹿児島大学
• Dissertation Number: 乙総論第39号
• Degree Type: 博士(医学)
• Subject Heading: wearable near-infrared spectroscopy; working memor; subjective well-being; lifestyle; university students; mental health
• Target Audience: 一般
• Note (General): 出版タイプ： VoR; 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨; Identification of social risk factors and the promotion of stress coping mechanisms and mental resilience are topics of interest in the field of mental health. The relationships between risk- or tolerability-associated factors and task-related hemodynamic responses in the prefrontal cortex (PFC) in adolescents may have important implications for mental health challenges. The purpose of this study was to investigate the relationship between task-related PFC hemodynamic activities and subjective well-being or lifestyle habits using wearable near-infrared spectroscopy (NIRS). In this study, after sample refinement to reduce heterogeneity, 20 university students were included in verbal working memory (VWM) task analyses and 21 were included in spatial working memory (SWM) task analyses. The task-related hemodynamic responses were detected using wearable NIRS. To assess the risk- or tolerability-associated factors, the levels of positive and negative affect were assessed using the Subjective Well-Being Inventory (SUBI) and lifestyle habits (such as gaming) were evaluated using a nine-item questionnaire. There was a positive correlation between SUBI positive affect and VWM task-related oxy-hemoglobin signal changes in the right dorsolateral PFC (DLPFC), underlining the significance of subjective well-being as an important independent emotional domain and suggesting the possibility of the differential objective evaluations of subjective well-being in the right PFC. Negative correlations between PFC activities during both VWM and SWM tasks at the left DLPFC and the number of game playing days in 1 week were also statistically significant, suggesting the presence of modality-nonspecific hemodynamic regulation by habitual game playing. Each correlation was still robust after the elimination of major confounding impacts. Although further replication studies are warranted to confirm these preliminary results, this investigation of the relationship between task-related PFC hemodynamic activities and emotional domains or lifestyle habits might have clinical significance with regard to primary prevention of mental health issues in university students. To our knowledge, this is the first demonstration of these relationships with the use of wearable NIRS, which enables measurement under near natural conditions and is easy to use in schools or workplaces. Yoichi Kawaike, Junko Nagata, Tamotsu Furuya, Chihaya Koriyama, Masayuki Nakamura and Akira Sano Working Memory-Related Prefrontal Hemodynamic Responses in University Students: A Correlation Study of Subjective Well-Being and Lifestyle Habits Frontiers in Behavioral Neuroscience 13,213 2019 https://doi.org/10.3389/fnbeh.2019.00213
• Format (IMT): application/pdf
• Source: Diss_川池_陽一_ISK39_2020 （fulltext）; https://ir.kagoshima-u.ac.jp/record/15472/files/Diss_%E5%B7%9D%E6%B1%A0_%E9%99%BD%E4%B8%80_ISK39_2020.pdf
• Access Restrictions: インターネット公開
• Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• Original Data Provider (Database): 鹿児島大学 : 鹿児島大学リポジトリ