口腔機能低下症とフレイル、サルコペニアおよび軽度認知障害との関係性 : 地域在住日本人高齢者の横断的研究

Material type: 博士論文

Author: 中村, 麻弥

Publisher: MDPI

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Material Format: Digital

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Name of awarding university/degree: 鹿児島大学,博士(歯学),Doctor of Philosophy in Dental Science

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Note (General)：: 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨Oral hypofunction is a new concept that addresses the oral function of older adults. Few studies have investigated t...

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Material Type: 博士論文
Title: 口腔機能低下症とフレイル、サルコペニアおよび軽度認知障害との関係性 : 地域在住日本人高齢者の横断的研究
Author/Editor: 中村, 麻弥
Author Heading: 中村, 麻弥ナカムラ, マヤ
Publication, Distribution, etc.: MDPI
Alternative Title: Association of Oral Hypofunction with Frailty, Sarcopenia, and Mild Cognitive Impairment : A Cross-Sectional Study of Community-Dwelling Japanese Older Adults
Degree grantor/type: 鹿児島大学
Date Granted: 2021-12-15
Dissertation Number: 甲総研第625号
Degree Type: 博士(歯学)
Doctor of Philosophy in Dental Science
Text Language Code: eng
Subject Heading: oral function
masticatory function
sarcopenia
Target Audience: 一般
Note (General): 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨
Oral hypofunction is a new concept that addresses the oral function of older adults. Few studies have investigated the relationship between oral hypofunction and general health conditions such as frailty, sarcopenia, and mild cognitive impairment. This paper explores these relationships in a large-scale, cross-sectional cohort study. The relationships of oral hypofunction with frailty, sarcopenia, and mild cognitive impairment were examined using data from 832 individuals who participated in the 2018 health survey of the residents of Tarumizu City, Kagoshima Prefecture, Japan. Individuals with frailty, sarcopenia, and mild cognitive impairment had significantly higher rates of oral hypofunction. Frailty was independently associated with deterioration of the swallowing function (odds ratio 2.56; 95% confidence interval, 1.26–5.20), and mild cognitive impairment was independently associated with reduced occlusal force (odds ratio 1.48; 95% confidence interval, 1.05–2.08) and decreased tongue pressure (odds ratio 1.77; 95% confidence interval, 1.28–2.43). There was no independent association found between sarcopenia and oral function. In conclusion, early intervention for related factors such as deterioration of the swallowing function in frailty, reduced occlusal force, and decreased tongue pressure in mild cognitive impairment could lead to the prevention of general hypofunction in older adults. Maya Nakamura, Tomofumi Hamada, Akihiko Tanaka, Keitaro Nishi, Kenichi Kume, Yuichi Goto, Mahiro Beppu, Hiroshi Hijioka, Yutaro Higashi, Hiroaki Tabata, Kazuki Mori, Yumiko Mishima, Yoshinori Uchino, Kouta Yamashiro, Yoshiaki Matsumura, Hyuma Makizako, Takuro Kubozono, Takayuki Tabira, Toshihiro Takenaka, Mitsuru Ohishi, Tsuyoshi Sugiura Association of Oral Hypofunction with Frailty, Sarcopenia, and Mild Cognitive Impairment: A Cross-Sectional Study of Community-Dwelling Japanese Older Adults Journal of Clinical Medicine 2021, 10(8), 1626 https://doi.org/10.3390/jcm10081626
Format (IMT): application/pdf
Source: Diss_中村_麻弥_ISK625_2021 （fulltext）
https://ir.kagoshima-u.ac.jp/record/16076/files/Diss_%E4%B8%AD%E6%9D%91_%E9%BA%BB%E5%BC%A5_ISK625_2021.pdf
Access Restrictions: インターネット公開
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 鹿児島大学 : 鹿児島大学リポジトリ